Friday 15^th September

Session I (Plenary): Welcome and hot topics in HD: structured discussion

9:00   Welcome and introduction

• On behalf of EHDN: Bernhard Landwehrmeyer
• On behalf of EHA: Beatrice De Schepper
• On behalf of High-Q: Allan Tobin & Ethan Signer

Hot topics in HD: structured discussion
Chair: Gillian Bates

9:15		Identifying targets for intervetion: controversies on primary screens - Aleksey Kazantsev
9:30		Genetic modifiers of HD: Is it worth looking? - Lesley Jones & Marcy MacDonald
9:45		Extrastriatal pathology in HD: important for the clinical phenotype? - Maria Björkqvist & Asa Petersen
10:00		Phenoconversion - a useful concept? - Ethan Signer & Allan Tobin
10:15		Symptom oriented treatment in HD: worth the effort? - Daniel Ecker, Joseph Priller & Bernhard Landwehrmeyer
10:30		Tea-/coffee break

Session II (Meeting rooms; see room assignment plan): working group meeting sessions

11:00		EHDN working group meeting sessions including a finger food lunch served in the respective meeting rooms
16:00		Tea/coffee break

Session III (Plenary): Summaries working group meetings
Plenary presentations by the lead facilitators of the working groups
Chair: Justo García de Yébenes

16:30		Behavioural Phenotype  (David Craufurd & Matthias Dose)
16:40		Biomarkers  (Sarah Tabrizi)
16:50		Brainbanking  (Justo García de Yébenes)
17:00		Cognitive Phenotype  (Anne-Catherine Bachoud-Lévi)
17:10		Genetic Modifiers  (Lesley Jones)
17:20		Health Economics  (Paul McCrone & Bernhard Landwehrmeyer)
17:30		Imaging  (Jan Kassubek & Beatriz Gomez-Anson)
17:40		Juvenile HD  (Oliver Quarrell)
17:50		Motor Phenotype  (Ralf Reilmann)
18:00		Neuroprotective Rx  (Christoph Kosinski & Berry Kremer)
18:10		Quality of Life  (Christiane Lohkamp)
18:20		Standard of Care  (Sheila Simpson)
18:30		Symptomatic Rx  (Daniel Ecker & Josef Priller)
19:30		Dinner at Duinse Polders

Saturday 16^th September

Session IV (Plenary): Perspectives on HD
Chair: David Craufurd

9:00		Towards a systematic review of treatment options in HD - Sir Michael Rawlins
9:30		A systematic search for disease-modifying therapies: CHDI - Janet Leeds
10:00		Saint Vitus dance in Europe - Axel Karenberg
10:30		Tea/coffee break

Session V (Plenary): Constitution of EHDN and Reports on Activities
Chair: Gillian Bates & Raymund Roos

11:00		Report on the activities of EHDN 9/05 - 9/06 - Bernhard Landwehrmeyer
11:15		A Constitution of the EHDN - Raymund Roos
11:45		Presentation of members standing for EC and SRC Vote on the constitution and first slate of members of EC and SRC
12:15		Outlook 2006-2007 and invitation to EHDN 2007/WCHD 2007 - Bernhard Landwehrmeyer
12:30		Lunch

Session VIa (Plenary): Pathogenesis of HD
Chair: Stefano Di Donato

14:00		Transcriptomics analysis in HD and its models: brain and peripheral tissues - Ruth Luthi-Carter
14:30		Mechanisms underlying transcriptional dysregulation in HD - Elena Cattaneo
15:00		Degrading huntingtin - David Rubinsztein
15:30		Disease pathways in HD: a collaborative effort - Christian Neri & Andreas Kremer
16:00		Tea/coffee break

Session VIb (Plenary): Developments in Clinical Sciences
Chair: Anne Rosser
 

16:30		Behavioral changes in HD and HD rodent models – Jenny Morton
16:50		Behavioral assessments in HD: towards improving the tools - David Craufurd
17:10		Motor assessments: new rater training, new read-outs – Ralf Reilmann
17:30		Prediagnostic stages of HD: recent findings – Jane Paulsen
17:50		Ongoing clinical studies and clinical studies in the making – Ira Shoulson, Anthony Clarke, Sandrine Humbert, Bernhard Landwehrmeyer
18:25		Closing remarks
18:30		End of  Conference
19:30		Reception at Pier
20:00		Formal Dinner at Pier

Sunday 17^th September

09:30	Excursion to Brugge

Wednesday 13^th September

10.00	Opening of registration desk
12:00	Lunch
13.30	Agenda Report from the board Report from the different member associations Co-operation EHA an EHDN Appointment of the EHA-representatives for the Executive Committee of the EHDN Planning Next European Meeting Other issues
17.30	Diner

Thursday 14^th September

9:00	Welcome Beatrice de Schepper, President EHA
9:15	Treatment of Huntington's Disease Prof. Patrick Cras, Neurologist
10:00	Coffee break
10:30	The speech pathologist and Huntington's Disease. Tanja Beeckman - Katja Batens, Speechtherapists
11:30	Lay organisations and professionals: love and marriage? Dr. Dirk Liessens, Psychiatrist
12:30	Lunch
14:00	Predictive, prenatal and pre-impalantion genetic testing in Europe, present and future Prof. Gerry Evers-Kiebooms, Dr. Marleen Decruyenaere
15:00	Coffee break
15:30	A mutual obligation in the care of patients with HD Prof. René Dom, Neurologist
16:15	Playing music about HD and Woody Guthrie Steve Smith
17:30	Dinner
19:00	Greetings on the occasion Minister Inge Vervotte, Flemish Minister for Welfare, Public Health and Family
20:00	Reception