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Euro Huntington's disease network [logo]
European HD Network Plenary Meeting - EHDN 2010 - Programme Saturday & Sunday -
Saturday, September 4th, 2010

Special Session: Huntington, History and Art

08:30-08:50   An Individual Pilgrimage to Prague
Christiane Lohkamp EHA (Stuttgart, Germany)

Plenary Session V: Scientific Presentations
Chair: Christian Néri (Paris, France)
Topic: Pathogenesis - Targets for Experimental Treatments in HD
09:00-09:20   Stress Response and Proteostasis
Rick Morimoto (Evanston, USA)
09:20-09:40   Sirtuins in Aging and Neurodegeneration
Ruth Luthi-Carter (Lausanne, Switzerland)
09:40-10:00   Antisense Oligonucleotide Therapy for HD
Don Cleveland (La Jolla, USA)
10:00-10:20   Is Huntingtin Also a Prion?
Ronald Melki (Gif-sur-Yvette, France)
10:20-11:00   Tea/Coffee Break

Plenary Session VI: Keynote Presentation
Chair: Gillian Bates (London, UK)
11:00-12:00   Animal Models for HD
William Yang (Los Angeles, USA)
12:30-14:00   Buffet Style Lunch
12:00-14:00   Poster Viewing & Guided Poster Tours
Chaired by Stephen Dunnett (Cardiff, UK),
Raymund Roos (Leiden, The Netherlands)

Short Communications II:
Chair: Sheila Simpson (Aberdeen, UK)
14:00-14:15   Autophagy Modulatin: a Potential Therapeutic Approach for HD
Robi Meray / Mike Poole Link Medicine (Cambridge, USA)
14:15-14:30   Developing RNAi Therapeutics Targeting Huntingtin with Direct CNS Delivery
Dinah Sah, Alnylam (Cambridge, USA)
14:30-14:45   Evaluation of the therapeutic potential of NP03, a low-dose lithium microemulsion, in the YAC128 mouse model of Huntington Disease
Mahmoud Pouladi (Vancouver, Canada)
14:45-15:00   Systematic identification of single nucleotide polymorphisms that modulate the age-at-onset of Huntington’s disease
Erich Wanker  (Berlin, Germany)

Plenary Session VII: Scientific Presentations
Chair: Berry Kremer (Groningen, The Netherlands)
Topic: Therapeutic Development Programme in HD
15:00-15:20   When to Enter Human Clinical Trials?
Ignacio Munoz-Sanjuan (Los Angeles, USA)
15:20-15:40   siRNAs for the Treatment of HD
Neil Aronin (Boston, USA)
15:40-16:00   ACR-16 for the Treatment of HD
Joakim Tedroff (Stockholm, Sweden)
16:00-16:20   DBS Surgical Trials in HD
Jan Vesper (Düsseldorf, Germany)
16:20-17:00   Tea/Coffee Break
17:00-18:00   Highlights
Ed Wild (London, UK),
Jeff Caroll (Vancouver, Canada),
Charles Sabine (Gloucestershire, UK)
18:00-18:30   Poster Awards
19:30-24:00   EHDN Plenary Dinner at the Municipal House

Sunday, September 5th, 2010

Breakfast Teaching Courses (parallel courses)

08:00-09:20   How and When to Diagnose HD
Sarah Tabrizi (London, UK),
Oliver Quarrell (Sheffield, UK)
08:00-09:20   How to Treat Huntington's Disease
Josef Priller (Berlin, Germany),
Raymund Roos (Leiden, The Netherlands)
08:00-09:20   Movement Disorders Phenomenology in HD
Ralf Reilmann (Münster, Germany)
Ferdinando Squitieri (Pozzilli, Italy)
08:00-09:20   Psychiatric Disorders in HD for Non-Psychiatrists
David Craufurd (Manchester, UK),
Erik van Duijn (Leiden, The Netherlands)
09:20-10:00   Tea/Coffee Break

Plenary Session VIII: Scientific Presentations
Chair: G. Bernhard Landwehrmeyer (Ulm, Germany)
Topic: Tools and Outcome to Monitor Disease Progression and Response to Therapy
10:00-10:20   Imaging Outcomes
Rachel Scahill (London, UK)
10:20-10:40   Motor phenotype Outcomes
Ralf Reilmann (Münster, Germany)
10:40-11:00   Cognitive Outcomes
Anne-Catherine Bachoud-Lévi (Créteil, France)
11:00-11:20   How Disease Modelling Can Inform Trial Design
John Warner (Princeton, USA)
11:20-12:00   Meeting Adjourn/Closing Remarks
Afternoon   Social Activities

Programme Thursday and Friday

Please note:
Since the meeting starts on Friday morning at 08.30, we highly recommend that you plan to arrive on Thursday, September 2nd, 2010.

Meals and refreshments will be provided during EHDN 2010 (i.e. from Friday until midday on Sunday; Sunday lunch will not be included) free of charge.