Thursday, September 13th, 2018
16:00-21:00 |
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Registration Desk |
Friday, September 14th, 2018
07:30-08:30 | |
Registration Desk |
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Welcome and Introduction Room: Hall E
08:30-09:00 |
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Jean-Marc Burgunder (Bern, Switzerland)
Astri Arnesen (Søgne, Norway)
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Keynote Session I:
Past, Present, Future Room: Hall E
Chair: Jean-Marc Burgunder (Bern, Switzerland) Co-chair: Astri Arnesen (EHA, Norway) |
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09:00-09:20 |
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Learning from the History of Huntington's Disease Peter Harper (Cardiff, UK)
slides Harper
Diary-of-the-Huntington-Gene-1993
Interview-with-Gusella-MacDonald |
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09:20-09:40 | |
Where are we Now Alexandra Dürr (Paris, France)
slides Durr |
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09:40-10:00 | |
The Silver Linings Playbook – A Future Outlook Ed Wild (London, UK)
slides Wild |
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10:00-10:20 | |
Living with Hope and Setbacks – a Family Perspective Astri Arnesen (Søgne, Norway) |
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10:20-10:30 | |
Panel discussion |
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10:30-11:00 |
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Tea/Coffee Break |
Plenary Session I: What's New in HD Biology: Insights into Pathogenic Pathways and Therapeutic Targets' Room: Hall E
Chair: Lesley Jones (Cardiff, UK) Co-chair: Erich Wanker (Berlin, Germany) |
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11:00-11:20 | |
Recent Breakthrough in Resolving the Structure of Huntingtin Stefan Kochanek (Ulm, Germany)
slides Kochanek |
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11:20-11:40 |
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Chaperone Biology and Huntington Aggregation
Harm Kampinga (Groningen, The Netherlands)
slides Kampinga |
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11:40-12:00 | |
Large-Scale Functional Analysis distinguishes Pathogenic, Non-Pathogenic, and Compensatory Transcriptional Changes in HD
Juan Botas (Houston, USA)
slides Botas |
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12:00-12:20 | |
Huntington’s Disease and the Genetics of CAG Repeat Expansions
Lesley Jones (Cardiff, UK)
slides Jones |
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12:20-12:30 | |
Panel discussion |
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Poster Viewing
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12:30-14:00 | |
Poster Viewing Room: Foyer |
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12:30-14:00 |
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Buffet Style Lunch |
| | Parallel Session I:
Parallel - Science Session: 'EHDN Projects' Room: Hall E
Chair: Anne Rosser (Cardiff, UK) Co-Chair: Patrick Weydt (Bonn, Germany) |
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14:00-14:10 | | Dysphagia in HD (Seed fund project) Falk Schradt (Ulm, Germany)
slides Schradt |
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14:10-14:20 | | Nucleolar Activity and mHtt (Seed Fund Project) Rosanna Parlato (Ulm, Germany)
slides Parlato |
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14:20-14:30 | | Isotype-Specific HDAC Inhibition (Seed Fund Project) Bob Lahue (Galway, Ireland)
slides Lahue |
| 14:30-14:40 | | CAG repeat length as a modifier (Datamining Project) Ahmad Aziz (Bonn, Germany)
slides Aziz |
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14:40-14:50 | | Quality-Adjusted Life-Years (QALYs) and Huntington’s Disease (Datamining Project) Colin Green (Exeter, UK)
slides Green | |
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Parallel - Clinical Practice Session: 'Care for HD' Room: Hall F2
Chair: Åsa Petersen (Lund, Sweden) Co-Chair: Astri Arnesen (Søgne, Norway)
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14:00-14:15 | | Implementation of Scottish National Care Framework John Eden (Paisley, UK)
slides Eden | |
14:15-14:30 | | Presence and Treatment of Psychiatric Symptoms in HD Karen Anderson (Washington D.C., USA)
slides Anderson | | 14:30-14:45 | | Caring for Carers Győző Pék (Debrecen, Hungary)
slides Pek | | 14:45-15:00 | | Discussion | | Short Communications I: 'Scientific Presentations: – selected from submissions' Room: Hall E Chair: Sandrine Humbert (Grenoble, France) Co-Chair: Jocelyne Caboche (Paris, France)
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| 15:15-16:15 | |
- Huntington's Disease Phenotypes and Disrupted Corticostriatal Connectivity Observed in a Novel iPSC-Derived in Vitro Co-Culture Model
Caroline S. Casey (London, UK) -
Determining the CAG Repeat Mosaic in Post-Mortem Human HD Brains
Heather Ging (London, UK)
slides Ging -
Understanding Cognitive Heterogeneity beyond Disease Burden in Huntington’s Disease
Alice White (Cambridge, UK)
slides White -
International Guidelines in Huntington’s Disease
Ann-Catherine Bachoud-Lévi (Creteil, France)
slides Bachoud-Lévi -
Allele specific gene editing for Huntington's Disease mediated by the KamiCas9 self-inactivating CRISPR/Cas9 system
Nicole Déglon (Lausanne, Switzerland)
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| 16:15-16:45 | | Tea/Coffee Break |
Plenary Session II: 'Dialing Huntingtin Down' Room: Hall E Chair: Douglas Macdonald (Los Angeles, USA) Co-chair: Nicole Deglon (Lausanne, Switzerland) |
| 16:45-17:05 | | Gene Editing Approaches for HD Therapy Beverly Davidson (Philadelphia, USA) | |
17:05-17:25 | | AAV5-miRNA HTT Lowering Therapy Pavlina Konstantinova (Amsterdam, The Netherlands)
slides Konstantinova |
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17:25-17:45 | | HTT lowering small molecule program Anuradha Bhattacharyya (New York, USA)
slides Bhattacharyya | |
17:45-18:00 | | Panel discussion
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Q&A Panel Discussion Room: Hall E Chair: Dina de Sousa (UK) Co-Chair: Patrick Weydt (Bonn, Germany) | | 18:15-18:45 | | Expert Answers to Questions of the Audience | | Dinner on your own
Workshop "Lumbar Puncture Skills" For Clinicans and Study Nurses Room: Hall F2
Chairs: Jan Lewerenz (Germany), Filipe Brogueira Rodrigues (UK) | | 19:15-20:15 | | Improve your LP skills (registration mandatory)
slides Rodrigues
slides Lewerenz |
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Meet the Expert For HD Family Members and Students 19:15-20:45 | | Several Meet the Expert Sessions |
| | | Mental Health Problems of HD David Craufurd, Hugh Rickards Language: English fully booked Room: 0.96-97 |
| | | Mental Health Problems of HD "Psychische Probleme bei HD: Ursachen, Symptome & Bewältigungsstrategien" - German session Alzbeta Mühlbäck, Nina Hofstetter Language: German fully booked Room: 0.16 |
| | | Everyday Life as an HD Gene Carrier Seth Rotberg, Michael Orth Languages: German, English fully booked Room: Hall N1 (Level 1) |
| | | Clinical Trials: What does it mean to be in a clinical trial Berry Kremer, Ralf Reilmann Languages: Dutch, English, German fully booked Room: Hall N2 (Level 1) |
| | | Young People and HD: Getting the support you need Bonnie Hennig-Trestman, Catherine Martin Languages: English fully booked Room: 0.14 |
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