O Sieci Huntington's Disease

Parallel Session I:

Parallel - Science Session:
'EHDN Projects'
Room: Hall E

Chair: Anne Rosser (Cardiff, UK) Co-Chair: Patrick Weydt (Bonn, Germany)

14:00-14:10		Dysphagia in HD (Seed fund project) Falk Schradt (Ulm, Germany) slides Schradt

14:10-14:20		Nucleolar Activity and mHtt (Seed Fund Project) Rosanna Parlato (Ulm, Germany) slides Parlato

14:20-14:30		Isotype-Specific HDAC Inhibition (Seed Fund Project) Bob Lahue (Galway, Ireland) slides Lahue

14:30-14:40		CAG repeat length as a modifier (Datamining Project) Ahmad Aziz (Bonn, Germany) slides Aziz

14:40-14:50		Quality-Adjusted Life-Years (QALYs) and Huntington’s Disease (Datamining Project) Colin Green (Exeter, UK) slides Green

Parallel - Clinical Practice Session:
'Care for HD'
Room: Hall F2

Chair: Åsa Petersen (Lund, Sweden) Co-Chair: Astri Arnesen (Søgne, Norway)

14:00-14:15		Implementation of Scottish National Care Framework John Eden (Paisley, UK) slides Eden

14:15-14:30		Presence and Treatment of Psychiatric Symptoms in HD Karen Anderson (Washington D.C., USA) slides Anderson

14:30-14:45		Caring for Carers Győző Pék (Debrecen, Hungary) slides Pek

14:45-15:00		Discussion

Short Communications I:
'Scientific Presentations: – selected from submissions'
Room: Hall E

Chair: Sandrine Humbert (Grenoble, France) Co-Chair: Jocelyne Caboche (Paris, France)

15:15-16:15		Huntington's Disease Phenotypes and Disrupted Corticostriatal Connectivity Observed in a Novel iPSC-Derived in Vitro Co-Culture Model Caroline S. Casey (London, UK) Determining the CAG Repeat Mosaic in Post-Mortem Human HD Brains Heather Ging (London, UK) slides Ging Understanding Cognitive Heterogeneity beyond Disease Burden in Huntington’s Disease Alice White (Cambridge, UK) slides White International Guidelines in Huntington’s Disease Ann-Catherine Bachoud-Lévi (Creteil, France) slides Bachoud-Lévi Allele specific gene editing for Huntington's Disease mediated by the KamiCas9 self-inactivating CRISPR/Cas9 system Nicole Déglon (Lausanne, Switzerland)

16:15-16:45		Tea/Coffee Break

Plenary Session II:
'Dialing Huntingtin Down'
Room: Hall E

Chair: Douglas Macdonald (Los Angeles, USA) Co-chair: Nicole Deglon (Lausanne, Switzerland)

16:45-17:05		Gene Editing Approaches for HD Therapy Beverly Davidson (Philadelphia, USA)

17:05-17:25		AAV5-miRNA HTT Lowering Therapy Pavlina Konstantinova (Amsterdam, The Netherlands) slides Konstantinova

17:25-17:45		HTT lowering small molecule program Anuradha Bhattacharyya (New York, USA) slides Bhattacharyya

17:45-18:00		Panel discussion

Q&A Panel Discussion
Room: Hall E

Chair: Dina de Sousa (UK) Co-Chair: Patrick Weydt (Bonn, Germany)

18:15-18:45		Expert Answers to Questions of the Audience

Dinner on your own

Workshop "Lumbar Puncture Skills"
For Clinicans and Study Nurses
Room: Hall F2

Chairs: Jan Lewerenz (Germany), Filipe Brogueira Rodrigues (UK)

19:15-20:15		Improve your LP skills (registration mandatory) slides Rodrigues slides Lewerenz

Meet the Expert
For HD Family Members and Students

19:15-20:45		Several Meet the Expert Sessions

		Mental Health Problems of HD David Craufurd, Hugh Rickards Language: English fully booked Room: 0.96-97

		Mental Health Problems of HD "Psychische Probleme bei HD: Ursachen, Symptome & Bewältigungsstrategien" - German session Alzbeta Mühlbäck, Nina Hofstetter Language: German fully booked Room: 0.16

		Everyday Life as an HD Gene Carrier Seth Rotberg, Michael Orth Languages: German, English fully booked Room: Hall N1 (Level 1)

		Clinical Trials: What does it mean to be in a clinical trial Berry Kremer, Ralf Reilmann Languages: Dutch, English, German fully booked Room: Hall N2 (Level 1)

		Young People and HD: Getting the support you need Bonnie Hennig-Trestman, Catherine Martin Languages: English fully booked Room: 0.14