TRACK-ON is an innovative multi-centre, multi-national prospective observational study with no experimental treatment that follows the successful previous clinical study TRACK-HD. The primary objective of TRACK-HD was to determine what combination of measures is the most sensitive for detecting change over the natural course of premanifest and early HD, with a view to validating these as potential outcome measures for use in future therapeutic trials. The four study sites of TRACK-ON are in London, Paris, Leiden and Vancouver. TRACK-On will continue to follow the premanifest and control groups from TRACK-HD for an additional 24 months and will assess a number of new imaging modalities and clinical outcome measures.

A Clinical Research Fellowship is available for a medical graduate with an interest in neurology or psychiatry to work under the direction of Dr. Blair R. Leavitt, based in the Department of Medical Genetics and the Division of Neurology, Department of Medicine (associate) at the University of British Columbia (UBC) in Vancouver, Canada.

The work will be in the field of Huntington’s disease, which is an inherited neurodegenerative disorder. The project is a clinical translational project, and is suitable for those seeking a career in clinical neuroscience. The working environment is collective and multidisciplinary. Enthusiasm, ability to be self-organised, an enquiring mind, vision and good clinical skills will all be necessary. The candidate will need to have good computer skills and be able to pick up mathematical statistical concepts.
Further information trackon-neuro-fellow-jobdescr-oct11 

PhD position available,
February 2011 or later,
Tuebingen at University of Tuebingen Department of Medical Genetics

Amongst others our Huntington working group studies the contribution of additional genetic modifiers to the pathology of the neurodegenerative Huntington disease. The projects itself aims to analyse the molecular mechanisms of an already identified protective modifier with the help of a transgenic mouse model in vivo. Techniques in this project will be the generation of a transgenic mouse model, phenotyping by behaviour testing, immunohistochemistry, analysis of protein expression as well as respirometric and photometric measurements. Experience in these fields are desirable, but will not be a prerequisite. We are looking for highly motivated PhD student with a master/diploma in biology or related life science, who enjoys innovative research and works with enthusiasm and team spirit. We provide a scientifically stimulating atmosphere, a technically well-equipped lab with, an interesting and diverse project and a friendly, international team. The position is available for an initial period of two years with a possibility of extension. Please send your application (including CV, a statement of research experience and interests, and names of at least 2 referees) to Dr. (email: silke.metzger@med.uni-tuebingen.de)

Junior Fellowship available,
December 2010, Milan
at Università degli Studi di Milano
Elena Cattaneo Laboratory
http://www.cattaneolab.it

NeuroStemcell (European Consortium for Stem Cell Therapy in Neurodegenerative Diseases) is a 4-year FP7 Integrated Project led by Coordinator Prof. Elena Cattaneo - University of Milan and Deputy Coordinator Prof. Anders Björklund - Lund University (additional information is available at www.neurostemcell.org or at www.cattaneolab.it) .

The goal of the project is to develop safe and validated stem cell lines capable of proper neuronal differentiation in vitro and in vivo, to be used in clinical trials and eventually in drug discovery.

Applicants should be highly motivated, communicative and inventive. At least one year of experimental work in molecular biology, fluency in English and a vivid interest in science are essential requirements.
 
Applicants should submit Curriculum Vitae by e-mail ( ). Please specify Œjunior fellowship application² in object.