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Projects - Proposals - Seed Funds -

NEXT Deadlines

The next deadline for seed fund applications will be:

November 1, at 11.59 PM CET (23.59 o'clock CET).

EHDN will award seed funds on a competitive basis amongst the submissions received at each deadline. Basic and clinical projects are welcome.
Proposals rejected at a previous round of applications will not be reconsidered. Amended versions will be treated as new submissions.

Submissions received after the deadline will not be considered and will only be reviewed during the next round. Recipients of seed funds cannot submit a new application unless they have provided a report that concludes their previously awarded seed fund project. Only European projects are eligible; the main PI has to be an EHDN regular member, based in Europe, and at least 50% of the funds must stay in Europe. All co-applicants have to be EHDN members (either regular or associated) and listed in the online submission form.

In the context of your research, questions about intellectual property can arise. Should you be awarded a seed fund, a contract with Ulm University as the legal representative of EHDN will need to be signed. This contract will address those questions as they pertain to for instance Disclosure of Inventions, Ownership of Intellectual Property, or a Covenant not to Seek Intellectual Property Protection. It is important for EHDN that everything that will come out of your project (e.g. data, results, assay, novel treatment, etc) can be shared for HD research and education.

Submission of Application for Seed Fund Project

Seed funds are intended to fast track the provision of limited funds to investigators for studies that are necessary in order to apply for larger grants from other organisations, or to estimate the power needed for e.g. clinical trials. Studies funded through this scheme should result in conclusive answers to the hypothesis underlying the study. The maximum sum available is €50.000.
All members can apply for seed funds. However, we especially encourage Working Groups to apply in order to encourage discussions and collaborations as well as to avoid unnecessary overlap between individual projects.

Applicants are requested to submit the following information (submission page):
  • Name, address, phone number of the applicant and co-applicants
  • Name of the institution of the applicant
  • Project title and summary (word limit 250 words)
  • a sufficiently detailed description of the project (see document below) including an outline of the statistical evaluation (including a power analysis if appropriate, can be uploaded)
  • date of application

For all genetic modifier studies it is mandatory to read the following document.

Guidelines for seed fund budget preparation

To apply for an EHDN seed fund project, you have to provide a detailed budget for your project. Please follow the specific guidelines:

Personnel costs:
List all positions that should be covered by the seed fund budget, with percentage of FTE and duration. As a non-profit organization, EHDN will only cover basic salary and related costs mandated by law. EHDN will not cover leaves of absence, vacations, Christmas or holiday funds, 13-month payments or other similar costs.
The budget should not include the salary of the PI or other researchers employed full-time by their institution.

Provide details of the materials necessary (costs per material, quantity, number of experiments)

Equipment costs:
EHDN does not pay for standard equipment. Specific equipment for a particular technique can be funded if this technique is essential for the planned project. In this case, provide an explanation of the need for the specific equipment. Any equipment purchased is the property of EHDN, and will be made available to other researchers upon completion of the project.

Animal costs:

Provide details on the species, the costs, and the quantity needed for the project.

Publication costs:
EHDN does not cover the costs of manuscript preparation and publication. Please discuss with EHDN where you intend to submit your manuscript for publications PRIOR to submission. EHDN encourages open access publications but will only consider any related costs upon request to the SBAC prior to submission to the journal.

Travel costs:
EHDN only covers travel costs for attending meetings and conferences if the research is being presented (poster, presentations). This is limited to one participant per meeting. Provide the name and date of meeting(s) you plan on attending.

Indirect/overhead costs:
These costs are limited to 3% of total budget

Other costs:
Give details and justification for any other costs.

Submission form to use for seed fund applications NEW FORM (August 2020)!

Check list: Please read this document in advance of the submission; some steps might take a few days (version 2019)

Is it a seed fund project?

Seed fund projects should exploit new and original ideas and therefore hold the potential to move HD research in novel directions. Reflecting this, the potential impact of the project leading to a new understanding of the disease and its treatment has high priority in the assessment.

A seed fund project does not necessarily lead to the full elucidation of a hypothesis, but should hold the potential to generate results based on which additional (more extensive) funding can be obtained.  The potential to generate more regular additional funding based on the help with the pro-posed grant should be outlined.

To show the novelty of the project, and to assure that the applicants are familiar with the HD literature, a review of the background for the project including reference to own work and of others is necessary.

Preliminary data may be included in the seed fund proposal to demonstrate the outcome of tested approaches using small sample sizes and to provide proof of concept or evidence to support a working hypothesis. Preliminary data may further be included to demonstrate the suitability and applicability of novel methodologies and technologies and the technical ability and competence of the research team.

Projects that are merely aiming to add more samples to a preliminary study using an already defined study design, or projects that are clearly a development of a previous publication basing on the same hypothesis, are examples of projects that are not considered to be seed fund projects.
Application review process

Every application will be reviewed by the Scientific and Bioethics Advisory Committee (SBAC).

The SBAC considers the aims, objectives, scientific and clinical merits of the applications, qualifications and capabilities of the investigators and the report of the bioethics advisor. Some criteria for the review of the applications are: Originality / "out-of-the-box", potential to generate more regular additional funding, potential impact, clear hypothesis and research question, background information, relevant previous and ongoing work considered, methods ade-quate to test hypothesis, resources and expertise to carry out this project suc-cessfully, statistics, costs, ethics and any other factors it deems appropriate.
SBAC’s recommendations will then be available to the EHDN Executive Committee. The final decision regarding endorsement of an application rests with the EHDN executive committee, also taking into account EHDN's Scientific Strategic Plan. Applicants will be informed about the progress of their application.
If applications are endorsed, access to data and/or biomaterials will be granted provided the applicants agree to/that:
  • The Data Disclosure Agreement, Material Transfer Agreement, or Research Agreement
  • The data from the EHDN database/biomaterials provided will be used for no other purposes than the ones specified in the proposal
  • The publication policy will be followed
  • A summary of the project (blurb) is posted on the ‘studies in progress’ area of the EHDN public website. The blurb should be no longer than 100 words and describe in simple words (comprehensible for the lay audience) the aims and methods of the project.
Progress reports

Applicants need to provide two reports summarising the work that has been accomplished.
  1. An interim report consisting of two parts:
    1. a summary of work accomplished in the last 6 months
    2. work planned for the next 6 months
  2. A final report with the results of the study. This should detail the objectives, material and methods, results, discussion and conclusions. If you have already submitted or published an abstract or publication, please upload it as well. Please do NOT use the publication itself as final report.