Investigators are expected to comply with the provisions of the Constitution and By-laws of the EHDN including the provisions relating to the conduct of clinical studies as laid down in Article 9, Publication and Authorship as laid down in Article 10 and Ethics and Conflict-of Interest as laid down in Article 11. Each site investigator retains at all times unrestricted access to all clinical data of all patients of her/his study site; the scientific exploitation of these data by site investigators does not require approval of EHDN. However, it is recommended that investigators keep EHDN informed of major ongoing scientific projects through the EHDN web site.
For submission of project proposals you need to be a regular or associated member of EHDN and to have a login to the EHDN web portal:
In order to request a membership fill out the application form.
If you want to submit a project application (please note: in order to submit a project application you need to have a login) go to the proposal file and click on the button ‘Add Proposal’. Once you have completed all entries in the ‘submission’ form press ‘Enter’. Your application will be given a project number once you open the ‘submission’ form. However, your application will only be processed if you press ‘Enter’. If you want your application to be removed please contact
. For help with the application please contact
Applications consist of two parts. The
first is a brief summary of no more than 250 words while the second is the full
application that can be uploaded on the project application ‘submission’ form.
Full applications should be structured into a background section, a material and methods section and a timeline for
the research. Background sections should be self-explanatory so that
additional research into the literature is not needed to understand the topic. This
section should detail the foundations that led to the rationale of the proposed
study. You should explain the need for research in
this area, and the rationale for the particular project you have in mind. Give
sufficient details of other past and current research to show that your aims
are scientifically justified, and to show that your work will add distinct
value to what is already known, or in progress. How well does the work fit with
other relevant HD research? Explain how the applicants work together, and
outline other major collaborations important for the research. If this is a
pilot work or proof of principle proposal (e.g. seed fund application), give a
brief description of the potential for subsequent proposals if your work is
successful. Describe briefly the potential ethical issues of any involvement of
people, human samples or personal data in the research proposal. The material
and methods section should detail how the work is going to be done. Give
details of the general experimental approaches, study designs, and techniques
you will use. This should include sufficient detail about the statistical
approach taken (see also section on genetic studies). Do you plan to
involve a statistician if your project requires complex statistical
analyses?If possible include power
calculations, or if it is a pilot study indicate the size of the pilot and how you
plan to use the data for further studies. Do you anticipate major scientific,
technical or organisational challenges and how will you deal with them?
Finally, applicants should put a timeline to their research.
Help (before, during and after)
EHDN offers help at all stages of a project application. If you need assistance please do not hesitate to contact Dr Michael Orth or Christine Capper-Loup.
Dr. Michael Orth
Principal Investigator, Coordination DE AT CH Ulm University Hospital, Neurology
Oberer Eselsberg 45/1 89081 Ulm Deutschland
+49 731 50063095
+49 731 50063082
Christine Capper-Loup, PhD
Scientific Project Manager Stiftung Siloah
Worbstrasse 316 3073 Gümligen Schweiz
+41 31 958 18 11
Substudies in REGISTRY
There are several substudies addressing specific research
questions (project proposals) planned within REGISTRY. Please view the document below for further information on them: